diff --git a/lang/python/python/Makefile b/lang/python/python/Makefile
index 20b8a1a7d..c545e327c 100644
--- a/lang/python/python/Makefile
+++ b/lang/python/python/Makefile
@@ -170,21 +170,29 @@ endef
 
 ifdef CONFIG_PACKAGE_python-setuptools
 define Build/Compile/python-setuptools
-	$(STAGING_DIR_HOSTPKG)/bin/pip install \
+	$(HOST_PYTHON_PIP) \
+		--disable-pip-version-check \
+		--cache-dir "$(DL_DIR)/pip-cache" \
+		install \
 		--ignore-installed \
-		--root=$(PKG_BUILD_DIR)/install-setuptools --prefix=. \
+		--root=$(PKG_BUILD_DIR)/install-setuptools \
+		--prefix=/usr \
 		$(PKG_BUILD_DIR)/Lib/ensurepip/_bundled/setuptools-$(PYTHON_SETUPTOOLS_VERSION)-py2.py3-none-any.whl
-	$(call PatchDir,$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON_VERSION)/site-packages,./patches-setuptools,)
+	$(call PatchDir,$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON_VERSION)/site-packages,./patches-setuptools,)
 endef
 endif # CONFIG_PACKAGE_python-setuptools
 
 ifdef CONFIG_PACKAGE_python-pip
 define Build/Compile/python-pip
-	$(STAGING_DIR_HOSTPKG)/bin/pip install \
+	$(HOST_PYTHON_PIP) \
+		--disable-pip-version-check \
+		--cache-dir "$(DL_DIR)/pip-cache" \
+		install \
 		--ignore-installed \
-		--root=$(PKG_BUILD_DIR)/install-pip --prefix=. \
+		--root=$(PKG_BUILD_DIR)/install-pip \
+		--prefix=/usr \
 		$(PKG_BUILD_DIR)/Lib/ensurepip/_bundled/pip-$(PYTHON_PIP_VERSION)-py2.py3-none-any.whl
-	$(call PatchDir,$(PKG_BUILD_DIR)/install-pip/lib/python$(PYTHON_VERSION)/site-packages,./patches-pip,)
+	$(call PatchDir,$(PKG_BUILD_DIR)/install-pip/usr/lib/python$(PYTHON_VERSION)/site-packages,./patches-pip,)
 endef
 endif # CONFIG_PACKAGE_python-pip
 
diff --git a/lang/python/python/files/python-package-pip.mk b/lang/python/python/files/python-package-pip.mk
index fecc5d901..0a8b69a6a 100644
--- a/lang/python/python/files/python-package-pip.mk
+++ b/lang/python/python/files/python-package-pip.mk
@@ -17,10 +17,10 @@ endef
 
 define PyPackage/python-pip/install
 	$(INSTALL_DIR) $(1)/usr/bin $(1)/usr/lib/python$(PYTHON_VERSION)/site-packages
-	$(CP) $(PKG_BUILD_DIR)/install-pip/bin/* $(1)/usr/bin
+	$(CP) $(PKG_BUILD_DIR)/install-pip/usr/bin/* $(1)/usr/bin
 	$(CP) \
-		$(PKG_BUILD_DIR)/install-pip/lib/python$(PYTHON_VERSION)/site-packages/pip \
-		$(PKG_BUILD_DIR)/install-pip/lib/python$(PYTHON_VERSION)/site-packages/pip-$(PYTHON_PIP_VERSION).dist-info \
+		$(PKG_BUILD_DIR)/install-pip/usr/lib/python$(PYTHON_VERSION)/site-packages/pip \
+		$(PKG_BUILD_DIR)/install-pip/usr/lib/python$(PYTHON_VERSION)/site-packages/pip-$(PYTHON_PIP_VERSION).dist-info \
 		$(1)/usr/lib/python$(PYTHON_VERSION)/site-packages/
 endef
 
diff --git a/lang/python/python/files/python-package-setuptools.mk b/lang/python/python/files/python-package-setuptools.mk
index c6d951a55..95951ecec 100644
--- a/lang/python/python/files/python-package-setuptools.mk
+++ b/lang/python/python/files/python-package-setuptools.mk
@@ -17,12 +17,12 @@ endef
 
 define PyPackage/python-setuptools/install
 	$(INSTALL_DIR) $(1)/usr/bin $(1)/usr/lib/python$(PYTHON_VERSION)/site-packages
-	$(CP) $(PKG_BUILD_DIR)/install-setuptools/bin/* $(1)/usr/bin
+	$(CP) $(PKG_BUILD_DIR)/install-setuptools/usr/bin/* $(1)/usr/bin
 	$(CP) \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON_VERSION)/site-packages/pkg_resources \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON_VERSION)/site-packages/setuptools \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON_VERSION)/site-packages/setuptools-$(PYTHON_SETUPTOOLS_VERSION).dist-info \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON_VERSION)/site-packages/easy_install.py \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON_VERSION)/site-packages/pkg_resources \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON_VERSION)/site-packages/setuptools \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON_VERSION)/site-packages/setuptools-$(PYTHON_SETUPTOOLS_VERSION).dist-info \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON_VERSION)/site-packages/easy_install.py \
 		$(1)/usr/lib/python$(PYTHON_VERSION)/site-packages
 endef
 
diff --git a/lang/python/python3/Makefile b/lang/python/python3/Makefile
index 5b3dcf355..e9468c97f 100644
--- a/lang/python/python3/Makefile
+++ b/lang/python/python3/Makefile
@@ -174,21 +174,29 @@ endef
 
 ifdef CONFIG_PACKAGE_python3-setuptools
 define Build/Compile/python3-setuptools
-	$(STAGING_DIR_HOSTPKG)/bin/pip3 install \
+	$(HOST_PYTHON3_PIP) \
+		--disable-pip-version-check \
+		--cache-dir "$(DL_DIR)/pip-cache" \
+		install \
 		--ignore-installed \
-		--root=$(PKG_BUILD_DIR)/install-setuptools --prefix=. \
+		--root=$(PKG_BUILD_DIR)/install-setuptools \
+		--prefix=/usr \
 		$(PKG_BUILD_DIR)/Lib/ensurepip/_bundled/setuptools-$(PYTHON3_SETUPTOOLS_VERSION)-py2.py3-none-any.whl
-	$(call PatchDir,$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON3_VERSION)/site-packages,./patches-setuptools,)
+	$(call PatchDir,$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON3_VERSION)/site-packages,./patches-setuptools,)
 endef
 endif # CONFIG_PACKAGE_python3-setuptools
 
 ifdef CONFIG_PACKAGE_python3-pip
 define Build/Compile/python3-pip
-	$(STAGING_DIR_HOSTPKG)/bin/pip3 install \
+	$(HOST_PYTHON3_PIP) \
+		--disable-pip-version-check \
+		--cache-dir "$(DL_DIR)/pip-cache" \
+		install \
 		--ignore-installed \
-		--root=$(PKG_BUILD_DIR)/install-pip --prefix=. \
+		--root=$(PKG_BUILD_DIR)/install-pip \
+		--prefix=/usr \
 		$(PKG_BUILD_DIR)/Lib/ensurepip/_bundled/pip-$(PYTHON3_PIP_VERSION)-py2.py3-none-any.whl
-	$(call PatchDir,$(PKG_BUILD_DIR)/install-pip/lib/python$(PYTHON3_VERSION)/site-packages,./patches-pip,)
+	$(call PatchDir,$(PKG_BUILD_DIR)/install-pip/usr/lib/python$(PYTHON3_VERSION)/site-packages,./patches-pip,)
 endef
 endif # CONFIG_PACKAGE_python3-pip
 
diff --git a/lang/python/python3/files/python3-package-pip.mk b/lang/python/python3/files/python3-package-pip.mk
index 9f942c660..a27d40a4e 100644
--- a/lang/python/python3/files/python3-package-pip.mk
+++ b/lang/python/python3/files/python3-package-pip.mk
@@ -17,15 +17,13 @@ endef
 
 define Py3Package/python3-pip/install
 	$(INSTALL_DIR) $(1)/usr/bin $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages
-	$(CP) $(PKG_BUILD_DIR)/install-pip/bin/pip3* $(1)/usr/bin
+	$(CP) $(PKG_BUILD_DIR)/install-pip/usr/bin/pip3* $(1)/usr/bin
 	$(CP) \
-		$(PKG_BUILD_DIR)/install-pip/lib/python$(PYTHON3_VERSION)/site-packages/pip \
-		$(PKG_BUILD_DIR)/install-pip/lib/python$(PYTHON3_VERSION)/site-packages/pip-$(PYTHON3_PIP_VERSION).dist-info \
+		$(PKG_BUILD_DIR)/install-pip/usr/lib/python$(PYTHON3_VERSION)/site-packages/pip \
+		$(PKG_BUILD_DIR)/install-pip/usr/lib/python$(PYTHON3_VERSION)/site-packages/pip-$(PYTHON3_PIP_VERSION).dist-info \
 		$(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages/
-	for _ in \$(seq 1 10) ; do \
-		find $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages/ -name __pycache__ -exec rm -rf {} \; || continue ; \
-		break ; \
-	done
+	find $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages/ -path '*/__pycache__/*' -delete
+	find $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages/ -type d -name __pycache__ -delete
 endef
 
 $(eval $(call Py3BasePackage,python3-pip, \
diff --git a/lang/python/python3/files/python3-package-setuptools.mk b/lang/python/python3/files/python3-package-setuptools.mk
index ce1fb5c11..b3ccce895 100644
--- a/lang/python/python3/files/python3-package-setuptools.mk
+++ b/lang/python/python3/files/python3-package-setuptools.mk
@@ -17,18 +17,16 @@ endef
 
 define Py3Package/python3-setuptools/install
 	$(INSTALL_DIR) $(1)/usr/bin $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages
-	$(CP) $(PKG_BUILD_DIR)/install-setuptools/bin/easy_install-* $(1)/usr/bin
+	$(CP) $(PKG_BUILD_DIR)/install-setuptools/usr/bin/easy_install-* $(1)/usr/bin
 	$(LN) easy_install-$(PYTHON3_VERSION) $(1)/usr/bin/easy_install-3
 	$(CP) \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON3_VERSION)/site-packages/pkg_resources \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON3_VERSION)/site-packages/setuptools \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON3_VERSION)/site-packages/setuptools-$(PYTHON3_SETUPTOOLS_VERSION).dist-info \
-		$(PKG_BUILD_DIR)/install-setuptools/lib/python$(PYTHON3_VERSION)/site-packages/easy_install.py \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON3_VERSION)/site-packages/pkg_resources \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON3_VERSION)/site-packages/setuptools \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON3_VERSION)/site-packages/setuptools-$(PYTHON3_SETUPTOOLS_VERSION).dist-info \
+		$(PKG_BUILD_DIR)/install-setuptools/usr/lib/python$(PYTHON3_VERSION)/site-packages/easy_install.py \
 		$(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages
-	for _ in \$(seq 1 10) ; do \
-		find $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages/ -name __pycache__ -exec rm -rf {} \; || continue ; \
-		break ; \
-	done
+	find $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages/ -path '*/__pycache__/*' -delete
+	find $(1)/usr/lib/python$(PYTHON3_VERSION)/site-packages/ -type d -name __pycache__ -delete
 endef
 
 $(eval $(call Py3BasePackage,python3-setuptools, \